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Collectively, these findings strongly suggest that exposure to NSW, induces systemic low-grade inflammation, likely through circadian disruption, and may contribute to the development of chronic diseases, including BC, highlighting the importance of occupational health strategies to mitigate these risks

Additionally, studies on simultaneous interventions of each process during hepatocyte engraftment are warranted, because the reason of low cell engraftment is multifactorial

Interestingly, the anti-apoptotic protein Bcl-2 binds to mutant SOD1 and aggregates in spinal cord mitochondria from patients and a mouse model of ALS, suggesting that mutant SOD1 may be toxic by depleting motor neurons of this anti-apoptotic protein (Pasinelli et al., 2004)

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