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Notably, the three-dimensional structure indicates that OsDHAR contains a broad, uncharged cleft between the 2-helix and the 3-helix as the putative binding site for non-native protein folding intermediates for its chaperone-like activity

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Vitamin B12 deficiency has also been associated with symptoms such as fatigue, changes in appetite, and neuropsychiatric issues, all of which overlap with symptoms of menopause