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Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation

Ishikawa F, Kaneko E, Sugimoto T et al (2014) A mitochondrial thioredoxin-sensitive mechanism regulates TGF--mediated gene expression associated with epithelial-mesenchymal transition

These regulatory mechanisms extend beyond energy metabolism to encompass broader biological significance

To explore whether the reduced ferroptosis sensitivity of NPC cells caused by EBV infection depends on the upregulated expression of GPX4, we used two specific shRNAs to knockdown endogenous GPX4 (Fig

It highlights the need for a more tailored approach to cancer therapy, taking into account the specific characteristics and vulnerabilities of different tumor cells