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Accessory criteria for ALPS were subdivided into primary (abnormal lymphocyte apoptosis assay and presence of pathogenic mutations in genes of the FAS pathway) and secondary criteria, which included characteristic histopathology, the combined presence of autoimmune cytopenia, polyclonal hypergamma-globulinemia, an ALPS-compatible family history, and the presence of elevated biomarkers, such as interleukin-10, interleukin-18, soluble FAS ligand, and vitamin B 12 (Oliveira et al., 2010)

Impaired intestinal barrier functions as driver for underlying oncologic diseases Although not as extensively studied as in other conditions, a disruption to the intestinal barrier may be a driver for oncologic diseases

AI applications in dentistry will succeed when they enhance clinical judgment, not replace it

While some patients experience positive results, recovery can involve stiffness, discomfort, or other complications

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