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Towards a systems understanding of MHC class I and MHC class II antigen presentation

Annexin V staining in live cells (PI ) assessed by flow cytometry

Alternatively, systemic abdominal injection allows the peptide to migrate to the carpal tunnel area

JAMA 301, 3951

The functions of amylin are complementary to insulin and to GLP-1 : Slows gastric emptying , similarly to GLP-1, but more strongly Suppresses glucagon , helps control postprandial glycemia Induces satiety , via the area postrema in the brainstem Regulates weight balance , long-term effect In type 2 diabetes amylin secretion deteriorates in parallel with insulin secretion , as the disease progresses, the -cells lose the ability to produce both hormones at once