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From the IC 50 value, the activity of Epothilone and glutathione-epothilone conjugates (1:4 M/M), was strongly higher than staurosporine by 3.2 and 8.3 folds, respectively, towards the HepG-2 cells

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[DOI] [PubMed] [Google Scholar] Katagiri D, Hamasaki Y, Doi K, Negishi K, Sugaya T, Nangaku M, Noiri E (2016) Interstitial renal fibrosis due to multiple cisplatin treatments is ameliorated by semicarbazide-sensitive amine oxidase inhibition

They can include: Your general health Your age Your physical conditioning Your lifestyle and physical activity level The medications you take Your weight The extent of the bone deformity The tears severity In most cases, milder injuries need less aggressive treatments than more moderate to severe tears or impingements