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It is especially critical in tissues with high oxidative stress

Moreover, a study published in the International Journal of Cancer by [22] in 2019 associated regular mushroom consumption with a lower risk of prostate cancer

doi: 10.1080/21655979.2021.1964158 229 XiaoXXuYMoschettaGAYuYFisherALAlfaro-MagallanesVMet al

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Although the enzymes necessary for glycolysis are found throughout the lens (see Cheng and Chylack116 for review), the first enzyme of the glycolytic pathway, hexokinase, which catalyzes the conversion of glucose to glucose-6-phosphate, is present at very low levels.117 The low level of hexokinase appears to be the rate-limiting factor for lens glucose metabolism and, therefore, restricts the generation of glucose-6-phosphate for both glycolysis and the hexose monophosphate shunt pathway118 (see later discussion)