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Description

85 Mechanistically, temsirolimus not only inhibits cancer progression by arresting the cell cycle in the G1 phase and subsequently impairing cell growth and proliferation but also indirectly constrains tumor angiogenesis by decreasing the level of HIF-1 and the production of vascular endothelial growth factor (VEGF)

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Subtle changes in the sequence combinations of these four bases in long stretches of DNA code contribute to genetic diversity among individuals in the population

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