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In gastric cancer, it induces ferroptosis by inhibiting GPX4 and GSS, thereby elevating lipid ROS levels

[PubMed] [Google Scholar] 26.Yu JS, Petersilge C, Sartoris DJ, Pathria MN, Resnick D: MR imaging of injuries of the extensor mechanism of the knee

For instance, deleting Pellino3 exacerbates insulin resistance by increasing pro-inflammatory macrophages, while inhibiting ITCH protects against steatohepatitis by promoting anti-inflammatory macrophages