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Although emerging therapies such as glucagon-like peptide-1 (GLP-1) analogues (e.g., semaglutide) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists (e.g., tirzepatide) have received clinical approval for obesity management, substantial demand persists for alternative or adjunctive therapies employing distinct mechanisms

In 2006, the authors tested the growth dynamics of four breast cancer cell lines exposed to BaP, and found that BaP exposure reduced cell proliferation via accumulation of cell cycle at S and G2/M phases, and induced p53-dependent cellular apoptosis

[DOI] [Google Scholar] 26.Jarosz M., Wierzejska R., Rychlik E., Szponar L., Sto K., Gieleciska I., Charzewska J., Pietra E., Mojska H., Matczuk E., et al