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Notably, in LNCaP prostate cancer cells, curcumin treatment resulted in a significant decline in global HDAC activity, possibly due to a reduction in HDAC8 expression

10.3390/life13010077 85 MancinoR.MartucciA.CesareoM.GianniniC.CorasanitiM

Vaishnavi, S

In allergic DILI, the drug or its intermediate metabolites become haptens that bind to proteins in hepatocytes and acquire antigenicity, triggering an immune response that leads to hepatocyte destruction

Table 3 summarizes the impact of physiological, psychological, social, and cultural factors on CVDs and proposes personalized nursing strategies for each patient