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Moreover, we showed that mAb M51 binds the MetE immunoprecipitated from Mtb culture supernatant by mAb M29 ( Figure 1C ), confirming (i) the good quality and the right conformation of the native recombinant protein that we produced and (ii) that these two high-specific mAbs recognize different, non-overlapping epitopes in the more Mtb-specific sequence of MetE

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This plasticity has important implications for cancer immunotherapy, as it raises the possibility of redirecting Tpex cells toward a memory fate rather than simply reinvigorating them within the exhaustion program

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Li JD, Feng W, Gallup M, Kim JH, Gum J, Kim Y, Basbaum C

Hofmeister discovered more than ten decades ago that differences in the solubility of proteins occur with a variety of different salts