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As long as 60 years ago, identification of the alternative IF-independent mechanism for vitamin B 12 absorption resulted in the discovery that if large enough doses were given, in the range of 100-100,000 g (although only 1% of the cyanocobalamin was absorbed), it was sufficient to provide the daily requirement

If IM was prescribed, use a longer needle next time or switch to a leaner site like the vastus lateralis

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