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Possible Underlying Conditions The main conditions your doctor should try to exclude are certain blood disorders and cancers (which break down cells and release B12), liver diseases (which release stored B12), and kidney diseases (which prevent the body from flushing out excess B12)

Target peptide quantification : allows construction of a direct cerebral pharmacokinetic curve, compared to plasma to calculate the brain/plasma ratio

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*Correspondence: Xuemei Tong [email protected] This article was submitted to Cellular Endocrinology, a section of the journal Frontiers in Endocrinology These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers