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doi: 10.1093/hmg/ddaa183 193

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To this end, humanized transgenic ( htg ) UGT1A wild type (WT) and htgUGT1A -SNP mice, containing a human haplotype of 10 common occurring UGT1A SNPs, were used

As methionine is the only precursor of cysteine in a cysteine-free diet, and cysteine is one of the three amino acids comprising glutathione, MR might logically be expected to reduce, rather than increase, glutathione levels

Possibly, the produced citrate is mainly transported into the cytosol and converted by ATP-dependent citrate lyase into OXA and acetyl-CoA and used for biosynthesis of aspartate and fatty acids, respectively