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Conclusion Although topical glutathione shows promise for dermatological applications, further larger randomized controlled trials with long-term follow-up are necessary to evaluate its utility more comprehensively in improving hyperpigmentation, erythema, and reducing free-radical damage

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The supernatant was mixed with nitro blue tetrazolium (NBT) in EDTA (0.1 mM, pH 7.4)

This shows that in PTSD patients, oxidative stress not only changes the activation pattern of the HPA axis, but may also interrupt adrenal gland function, further stimulating a vicious cycle of stress responses