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Although all isoforms promote excitatory synaptic transmission, their subcellular localization varies significantly, with NLGN3 diffusely distributed in dendrites and NLGN3A1A2 enriched in spines, revealing that splicing-dependent isoform distribution specificity is a key molecular mechanism for bidirectional regulation of inhibitory synapses (85)

Although not all patients with endometriosis have metabolic abnormalities, those who do may experience indirect symptom improvements through improved metabolic balance

By inhibiting these pathways, quercetin effectively reduces triglyceride accumulation within hepatocytes and improves overall lipid profiles

TB-500 is studied for actin-binding and cytoskeletal-remodelling activity that supports cell migration to sites of damage

Neurology 98 , e1304e1314 (2022)