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Studied for localized hypertrophy: The community interest is site-specific muscle growth from near-muscle injection a plausible extrapolation from the pharmacology that has not been confirmed in controlled human studies

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Do either of these have long-term outcome data

Regarding DM-associated gastrointestinal pathophysiology, studies demonstrate hyperglycemia-driven systemic inflammation through three key mechanisms: (1) Downregulation of intestinal tight junction proteins (e.g., ZO-1) enhances gut permeability, enabling systemic translocation of pathogen-associated molecular patterns (PAMPs, e.g., LPS)

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