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The United States Food and Drug Administration has approved Ivosidenib (AG-120) for treating mutant IDH1 cholangiocarcinoma and certain hematological malignancies[87]

Yu T, Zhao L, Huang X, Ma C, Wang Y, Zhang J, et al

11 , e2207435 (2024)

Psychiatry 3, e299

As an alternative, WS supplementation may also alter the activity of critical enzymes in physiological processes linked to the creation of testosterone, increasing levels in people with low cortisol levels [11, 12, 160], but not in people with high cortisol levels [29]