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It is noteworthy that supplementation with iron-modulating agents does not effectively reduce hepatic iron stores and is anticipated to garner significant interest as a novel therapeutic strategy for addressing the pathogenesis of hemochromatosis [108, 109]

The nomenclature of CYP enzymes includes the root CYP followed by a number that designates the family, then a letter designating the subfamily, and then another number to identify the specific gene, which differs from species to species

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Therefore, whether ferroptosis is beneficial for cancer immunotherapy remains unclear because of the contrasting results obtained to date immune checkpoint inhibitors have been used 84,115,116

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