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NO activates soluble guanylate cyclase [174], resulting in the generation of cGMP, which in turn activates cGKI [175]

10.1523/JNEUROSCI.17-21-08363.1997 107 GagliardiR

Although the levels of citrate and pyruvate in PDXG1 was decreased compared with PC, the other intermediates of TCA like succinate, malate and fumarate did not decrease, indicating that substrates of TCA were replenished by anaplerosis pathways