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Description

While generally mild, adverse events related to vorinostat can include thrombosis, QT interval prolongation, and potentially fatal ventricular tachycardia or torsional tachycardia

MOTS-c improves metabolic flexibility, insulin sensitivity, and cellular energy regulation by acting on mitochondrial signaling

However, much of the data supporting the contraindication and interaction is based on the use of intravenous methylene blue, or extrapolation of similar drugs that work on MAOIs