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2013;8:e81937

Yogindran S, Rajam MV (2015) RNAi for crop improvement

10.1016/j.phymed.2025.157677 Phytomedicine 30 TanJ

In particular, Nrf2 coordinates the expression of enzymes involved in the biosynthesis and recycling of glutathione (GSH), including glutamate-cysteine ligase catalytic and modifier subunits (GCLC and GCLM), glutathione synthetase (GSS), and the cystine/glutamate antiporter component SLC7A11

It also showed beneficial impacts on glycemic and blood pressure control as well as lipid metabolism in hypertensive patients without serious adverse effects such as liver and kidney dysfunction [181]