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The cell culture experiments in this study indicate that NFT concentrations in the range of 550 M were optimal for the induction of de novo glutathione synthesis

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Given the association between hypoxia and MS pathogenesis, it is tempting to speculate that regulating HIF-1 may be possible to improve the local hypoxic microenvironment in MS patients, reducing vascular inflammation and fibrosis, and ultimately alleviating clinical symptoms

For example, Ibrahim et al

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