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The peptide itself is identical

Decreased NAD + levels can impair the efficiency of the mitochondrial respiratory chain, resulting in reduced energy production, which may exacerbate obesity and related metabolic disorders (Amjad et al., 2021)

Our explainer on how tirzepatide influences incretin pathways and the overview at what tirzepatide (Mounjaro/Zepbound) is and how it works walk through the receptor pharmacology

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B12 deficiency is quite common in both the US and UK, affecting around 6% of people aged under 60, and nearly 20% of those 60 and over