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3.2 In vivo models Similar to other brain malignancies, the study of MB frequently relies on established cell lines, from murine and/or human origin, and PDX models

[DOI] [PMC free article] [PubMed] [Google Scholar] Lee A.H., Scapa E.F., Cohen D.E., Glimcher L.H

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The mainstay of therapy is intensive behavioral interventiongiven for 20 or more hours per weekwhich has been shown to produce important benefits, but response to treatment varies widely, and it is challenging to predict which children will respond [5]