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Thus, ERAD is expected to play a crucial role in the pathogenesis of various diseases, including cancer, metabolic and genetic disorders, neurodegenerative diseases, and therapeutics

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[DOI] [PubMed] [Google Scholar] Han B., Luo G., Shi Z.Z., Barrios R., Atwood D., Liu W., Habib G.M., Sifers R.N., Corry D.B., Lieberman M.W

Other miRNAs, like miR-15, miR-20a/b, or miR-101 modulate cell cycle and senescence pathways, often targeting epigenetic regulators like EZH2, thus contributing to UV-induced aging and tumor suppression mechanisms 109