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G6PD mahidol, a common deficient variant in South East Asia is caused by a (163)glycine-serine mutation

The cholesterol synthesis pathway is also significantly altered in astrocytes from aged mice (24-months-old), likely contributing to the observed decline of cholesterol in the aged brain and potentially hindering production of myelin (Boisvert et al., 2018

However, the long-term use of ketoconazole may lead to liver toxicity and hypogonadism [165], presenting challenges for clinical application in SS treatment

PQQ, or pyrroloquinoline quinone, is a compound made by bacteria that helps them digest alcohol and sugar to make energy

10.19939/j.cnki.1672-2809.2025.05.18 52 LiX.SunR.LiuR