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2-O--d-Glucopyranosyl-l-ascorbic Acid, an Ascorbic Acid Derivative Isolated from the Fruits of Lycium Barbarum L., Modulates Gut Microbiota and Palliates Colitis in Dextran Sodium Sulfate-Induced Colitis in Mice

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In summary, based on the characteristic metabolic reprogramming of tumor cells, combination therapies that simultaneously target multiple metabolic pathways or synergize with other treatment modalities represent a systematic strategy to overcome the limitations of monotherapy, suppress tumor adaptation, and ultimately increase therapeutic efficacy