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The authors framed the data as first clear evidence that NNMT inhibitors constitute a viable pharmacological approach to enhance regenerative capacity in aged skeletal muscle

NNMT is highly expressed in fat tissue, which has made its inhibition a focus of metabolic research

This is often due to limited dietary intake, malabsorption, medical conditions, or the use of B12-depleting medications ( Vitamin B12 deficiency is determined as follows ( Because the ability to absorb B12 from food declines with age, deficiency is more common in older adults

Consistency matters significantlymissing doses allows levels to drop