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Consent for Publication Consent to publication was obtained from all participants included in the study

Moreover, despite the fact that Paracoccidioides cells have and express other Sods (Sod1, Sod2, Sod4, Sod5, and Sod6) it is possible that Sod3 is potent enough to counteract exogenously-produced ROS under the studied conditions

AMPK activation inhibits ROS production induced by mitochondrial dysfunction and endoplasmic reticulum stress, reduces the generation of pro-inflammatory factors caused by dyslipidemia and hyperglycemia, and prevents vascular endothelial dysfunction by increasing nitric oxide (NO) bioavailability (71, 72)

As one of the first microorganisms to colonize the human gut and to accompany humans throughout their lives, bifidobacteria have a wide range of benefits for human health 8

HIV-1 Tat activates Akt/mTORC1 pathway and AICDA expression by downregulating its transcriptional inhibitors in B cells