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doi: 10.1016/j.ijbiomac.2023.126013

DEG treatment decreased 5hmC and increased H3K4me3, similarly to ML226 treatment, but had no effect on HIF-1 stabilization (Fig

329,330 In degenerative joint diseases like OA, the metabolic balance of chondrocytes is disrupted, leading to the overproduction of degrading enzymes and inflammatory mediators, including iNOS, MMP-13, and ADAMTS5 (a disintegrin and metalloproteinase with thrombospondin motifs 5), which participate in cartilage degradation and inflammatory processes

Scialabba C, Puleio R, Peddis D, Varvaro G, Calandra P, Cassata G, Cicero L, Licciardi M, Giammona G (2017) Folate targeted coated SPIONs as efficient tool for MRI

Ecdysterone improves oxidative damage induced by acute ischemic stroke via inhibiting ferroptosis in neurons through ACSL4