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1719-A BH3-ONLY PROTEINS REGULATE HEPATOCYTE APOPTOSIS AND APOPTOSIS-RELATED LIVER INJURY Shinnosuke Kudo 1 , Hayato Hikita 1 , Yoshinobu Saito 1 , Takahiro Kodama 2 , Tomohide Tatsumi 1 and Tetsuo Takehara 2 , (1)Osaka University, Graduate School of Medicine, (2)Osaka University Graduate School of Medicine Background: Continuous hepatocyte apoptosis with the activation of pro-apoptotic Bcl-2 family proteins, Bak/Bax, is observed in various chronic liver diseases like non-alcoholic steatohepatitis (NASH)

Propofol promotes neuronal recovery by inhibiting autophagy in neuronal injury through the Ca 2+ /calmodulin-dependent protein kinase kinase /AMPK/mTOR pathway (Sun et al., 2018)