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S2C), confirming that loss of Lcn2 reduces osteocytes vulnerability to ferroptotic stress

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Additionally, PDAC cells-derived galectin-3 has been reported to activate PSC and enhance ECM production through activation of the NF-B signaling pathway, contributing to the crosstalk between the two cells and remodeling of the desmoplastic microenvironment 20

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Differences in neurometabolite concentrations between Crohns disease patients and healthy controls No significant differences were found in a regression analysis comparing absolute concentrations of neurometabolites in Crohns disease patients and healthy controls (Figure 2 and Supplementary Table 1)