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This mutation leads to detrimental phenotypes such as premature aging, senescence, immune deficiency, and neurodegeneration 111,288

Multiple studies have found that patients receiving cortisone injections often experience worse outcomes at 6 and 12 months compared to those who received placebo injections or physical therapy alone

Thats what we like to see, is somebody who has a big old injury and is able to work through it, and we build tissue tolerance back up, and being able to do all that, I think that is key