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475,476 In the phase 3 GeparQuinto trial, bevacizumab was added to patients treated with anthracycline and taxane, which significantly improved the pCR rate in BRCA1 /2 mutation carriers

Banaszkiewicz T, Biaek A, Tokarz A, Kaszperuk K

48,53 Once synthesized in the cytosol, these precursor proteins, bearing distinctive amino-terminal cleavable targeting motifs, are recognized and translocated by the translocase of the outer/inner membrane (TOM/TIM) complex, such as TOM20, TOM22, TOM40, and TIM23