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The anti-inflammatory effects of -3 fatty acids are well-established (44, 45), attributed mainly to (1) their conversion into pro-resolving mediators like lipid regulators, resolvins, and anti-inflammatory mediators, which inhibit pro-inflammatory factors like TNF-a, IL-1, and NF-B, and (2) the inhibition of -6 fatty acids from converting into pro-inflammatory substances like prostaglandins (PG) E2 and leukotrienes (LT) B4

Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

Notably, even in the absence of growth factor signaling, serum induces cell migration, suggesting the presence of unidentified stimulatory factors 21,22

in particular, mutations of NLGN3 and NLGN4 genes, both located on the chromosome X, have been found in some ASD patients 37

Ungvari Z, Wolin MS, Csiszar A