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One millimolar MGO was added to 0.5 mg BSA (in 500 l of PBS, pH 8.0), and the pH of the mixture was adjusted to 89 by adding 1 M NaOH

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14.2 Prevention of Postmenopausal Osteoporosis The efficacy and safety of Reclast in postmenopausal women with osteopenia (low bone mass) was assessed in a 2-year randomized, multi-center, double-blind, placebo-controlled study of 581 postmenopausal women aged greater than or equal to 45 years, who were stratified by years since menopause: Stratum I women less than 5 years from menopause (n=224)

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