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About the Director of Osteopathic Education Anne Darby, DO, is the Director of Osteopathic Education for the Family and Community Medicine Residency (Hershey, Pa)

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When used in humans, oral NAC is metabolized into cysteine in the intestine, and this cysteine is oxidized to cystine, which is then transported into cells to be consumed as an essential precursor for glutathione synthesis [125]

Therefore, this review aims to provide a comprehensive overview of the current evidence on how nutraceutical supplementation influences cytokine-driven immunological mechanisms in NAFLD/MASLD by integrating findings from both clinical and preclinical studies