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Additionally, ketamine activates the NLRP3 inflammasome, inducing caspase-1 activation and neuronal pyroptosis, further contributing to neuroinflammation in regions, such as the hippocampus and prefrontal cortex (Zhang et al., 2021)

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Other compounds, classified as senolytics, have been described to influence senescent cell viability

Limitations of This Comparison Several structural limitations constrain everything above, and honest readers should keep them in view: No head-to-head data