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The finding that acetate supplementation restores LEC markers and rescues the corneal lymphangiogenesis deficits of the LEC-Atg5 / mice, unravels the key regulatory role that autophagy plays in the metabolic homeostasis of lymphatic vessels

Palladium-assisted removal of a solubilizing tag from a Cys side chain to facilitate peptide and protein synthesis

Targeting one carbon metabolism with an antimetabolite disrupts pyrimidine homeostasis and induces nucleotide overflow

Unbiased assessment of APR-246 responsive p53 mutants in ovarian cancer