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The FDA black box warning on antidepressant suicide risk in young adults: more harm than benefits

doi:10.1016/s0006-2952(02)01176-0 10

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By 2008, the proposition that anti-manic drugs attenuated kinases for their therapeutic effect was put forth, including key kinases GSK3 (inhibited by lithium, valproate and ECT) and PKC (inhibited by chronic lithium, valproate and ECT) (Machado-Vieira et al., 2023)