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6,7 Conversely, nonsurgical periodontal therapy such as scaling and root planing have demonstrated an increase in glutathione levels, suggestive of an improved antioxidant status and reduction in oxidative stress, perhaps partly due to a reduction in the proteolytic activity of bacteria and reductions in inflammation

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the 2.88 mg/kg amount produced the larger effect on neuroinflammatory cytokine markers and PI3K/AKT pathway activation [5]

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