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Normalization of vitamin B12 (B12) levels achieved following 1000 mcg oral Eligen B12 therapy: a clinical study comparing the efficacy and safety of oral B12 therapy versus intramuscular (IM) therapy

This makes the homocysteine level a useful but non-specific test, which tells me how the methylation cycle is working

The predominant mean half-life of free and total cobalamins-(III) was found to be approximately 26 to 31 hours at both the 5 g and 10 g dose level

Revista brasileira de reumatologia

Serious adverse events have not been widely reported, but this may reflect the relatively small number of people who have used the compound and the limited reporting mechanisms available