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doi: 10.1002/14651858.CD003373

Neuron 2012

They can effectively reduce hair loss, promote regrowth, and enhance overall hair quality

Acts as a macrophage DAMP molecule like MSU crystals to promote hyperuricemia and its complications ( via NLRP3 inflammasomes in macrophages ( UA activates phagocytosis by macrophages MSU crystals promote phagocytosis by macrophages