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In Fungal genomics

4 There is no universal standard as to how these combination treatments can be used, which has led to many differing treatment regimens

A mitochondria-targeted covalent organic framework (COF) prodrug that is selectively activated by high intramitochondrial GSH levels was shown to trigger catalase collapse within the organelle, thereby amplifying local chemodynamic therapy (CDT) through enhanced ROS accumulation and mitochondrial dysfunction