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These simulations indicate that within highly confined matrices, such as those encountered in vivo, the force resulting from the pressure drop across the cell dominates over the total shear force [230]

A.GrahamL.VolchkovP.et al

Nature 606 , 930936 (2022)

The extracellular matrix (ECM) plays a crucial role in the process of tissue regeneration, participating in the proliferation, migration, and differentiation of various cells