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It has been isolated in many different evolutionarily distant organisms such as bacteria (4), plants like Zea mays (5), invertebrates like Dendrocoelum lacteum or Drosophila melanogaster (6, 7)

Therefore, we concluded that activation of p53 effectively prevents APAP accumulation by promoting APAP metabolism and elimination

The operating conditions were 30 C with 50 mM potassium dihydrogen phosphate buffer (pH 2.8) and 10 mM sodium 1-heptanesulfonate as the mobile phase at a flow rate of 1.0 mL/min, and detection was performed with an ultraviolet detector SPD-20A (Shimadzu) at 210 nm

For each fluorescence intensity obtained from the WT-pGFPR01 incubated at a certain pH, a fluorescent background was subtracted from the WT cells incubated at the same pH

The toxicity of iron may be due to its localization, biochemical form or cell ability to prevent the generation and propagation of iron