If heartburn has been well-controlled at 10mg with your management protocol, adding a slightly more aggressive version of the same approach (perhaps adding melatonin or switching from H2 blockers to PPIs) often handles the 12.5mg and 15mg transitions
You might hear about different kinds of B12 used in injections
In humans, lower levels of the de novo NAD + synthesis precursor Trp have been observed in blood samples of PD patients, indicating disruption of the kynurenine pathway 276,277
This blend is designed to give your body what it needs to: Convert food into usable energy more efficiently Support a healthy metabolic rate Promote better fat breakdown and utilization Enhance overall wellbeing Vitamin B12 plays a key role in red blood cell production, nerve health, and energy metabolism
How to supplement when B12 tests are high Be sure you remove all sources of synthetic cyanocobalamin from your diet (supplements & fortified foods) Consider supplementing with iodine, selenium, and molybdenum which helps activate B2 (a B12 transport helper) Consider supplementing with an active B2 form (Riboflavin-5-Phosphate) - a B12 transport cofactor Consider taking intrinsic factor which helps the gut better absorb B12 Consider pulsing 4.5 mg of lithium orotate (2-3x per week) - helps the B12 transport Only supplement with bioidentical active B12 forms - hydroxocobalamin, methylcobalamin, adenosylcobalamin I know my specific COMT & VDR Taq gene details