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Current insights into glutathione depletion in adult septic patients

Our body counteracts oxidative stress and free radicals with antioxidant systems that include endogenous antioxidants like GSH and exogenous antioxidants we may get from our diet

The biological scissors cut glutathione into its constituent amino acidscysteine, glutamic acid, and glycinemaking it useless as a whole antioxidant

Unlike acetyl glutathione, reduced glutathione is in the bio active form, for best absorption

This intense inflammation is associated with damaging systemic events like oxidative stress, dysregulation of iron homeostasis, hypercoagulability and thrombus formation, acute respiratory distress syndrome, uncontrolled inflammation and organ failure (251257) (Figure 8)